General Cell Lines and Cell Cultures
ATCC Niallia circulans
Niallia circulans strain AMC 732 is a quality control strain that is included in the bioMerieux VITEK 2 - Bacillus (BCL) Card Quality Control Organism Set.
Eurofins Discoverx PathHunter CHO-K1 LXRα Nuclear Translocation Cell Line, 2 vials. (93-0215C2)
The PathHunter LXRα Nuclear Translocation cell line is a stable, engineered cell line for use in studying drug candidates affecting NHR activation and nuclear translocation. This cell line enables assessment of ligand (e.g. oxysterols) based NHR activation via detection of resulting LXRα nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged LXRα NHR and nuclear localized EA. Upon activation of LXRα, induced nuclear translocation leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
Eurofins Discoverx PathHunter CHO-K1 GLP2R β-Arrestin Cell Line, 2 vials. (93-0572C2)
The PathHunter GLP2R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. GLP-2) based activation of GLP2R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GLP2R and EA-tagged β-Arrestin-2. Activation of GLP2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Sp2/0-Ag14Non-secreting Hybridoma Mouse (Mus musculus)
Sp2/0-Ag14 is a B lymphocyte cell line that was isolated from the spleen of a mouse. This cell line was deposited by G Kohler and can be used in immunology research.
Cell Biologics Cynomolgus Monkey Primary Bronchial Epithelial Cells, Vial
Cynomolgus Monkey Primary Bronchial Epithelial Cells can be used for the assay of cell-cell interaction, adhesion, PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.
ATCC HCC1419; Breast Ductal Carcinoma; Human (Homo sapiens)
HCC1419 is an epithelial cell that was isolated from the mammary gland of a 42-year-old, Hispanic female patient with dutcal carcinoma TNM stage IIIA, grade 3. The cell was deposited by AF Gazdar and AK Virmani and can be used in cancer research.
Eurofins Discoverx ChemiScreen TRH Thyrotropin-Releasing Hormone Receptor Stable Cell Line, 2 vials. (HTS126C)
The ChemiScreen TRH Thyrotropin-Releasing Hormone Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TRH) based activation of TRHR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TRHR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TRHR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiBrite FP Prostanoid Receptor Stable Cell Line, 2 vials. (HTS093L)
The ChemiBrite FP Prostanoid Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin F2a) based activation of PTGFR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGFR, a naturally Gq coupled GPCR. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of PTGFR, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay δ Opioid Receptor Frozen Cells, 2 Vials of Cells. (HTS100RTA)
The Ready-to-Assay δ Opioid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. DADLE, DPDPE) based activation of OPRD1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses OPRD1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of OPRD1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.